What's Inside
Eight chapters, plus key takeaways
Why Adherence Remains Pharma's Biggest Challenge
Why patients disengage — cost, side effects, treatment fatigue, emotional concerns — and what makes pharma's adherence problem structurally unique.
Understanding the Real-Time Patient
The behavioral signals patients generate continuously, and the Intelligent Adherence Flywheel that turns them into interventions.
Moving Beyond Reminders to Intelligent Journeys
Action-based versus intent-based engagement, and a four-stage adherence maturity model from reactive to intelligent orchestration.
AI as the Intelligence Layer
The next-best-action framework: who needs support, what support is relevant, which channel, and when the intervention should land.
Building Trust in Personalized Healthcare
Transparency, accountability and governance — making personalization feel supportive rather than intrusive under HIPAA and GDPR.
Orchestrating Connected Patient Journeys
The fragmentation problem, from refill reminders arriving after a refill to patients repeating themselves across touchpoints.
Measuring Adherence Success
Four dimensions — patient outcomes, engagement effectiveness, operational efficiency and business impact — including MPR and PDC.
The Future of Adherence
Digital therapeutics, connected health devices, generative AI assistants, and predictive autonomous orchestration.
of patients with chronic conditions do not take medications as prescribed — contributing an estimated $100–300 billion in avoidable healthcare costs each year, with the first year of therapy the most vulnerable period.
What You'll Take Away
Five things you can act on
A four-stage maturity model to locate where your adherence programme actually sits
A next-best-action framework built around four questions asked continuously, not once
Why intent-based engagement outperforms reminder volume, with a worked patient example
Measurement across four dimensions, connecting engagement activity to clinical outcomes
Governance that keeps AI-driven patient engagement explainable and auditable
Who It's For
Across the patient support ecosystem